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Cost per Mille is another way of saying cost per 1000 and is regularly used when it comes to online advertising. Any sort of advertising that will reach a lot of people can be calculated this way and as well as online, it can be used for television, radio and the printed word. It is the way that the true cost of an advertising campaign can be calculated. The way that this works is easy. Normally referred to as the CPM, the cost is worked out by dividing the cost of the advertising campaign by the number of people who became involved as a result of it.